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Postion:Product Catalog >API>Antibiotics>Cephalosporins Drugs>Cefoperazone
Cefoperazone
  • Cefoperazone

Cefoperazone

Price $3
Package 3KG
Min. Order: 1KG
Supply Ability: 100kg
Update Time: 2019-08-08

Product Details

Product Name: Cefoperazone CAS No.: 62893-19-0
Min. Order: 1KG Purity: 99%
Supply Ability: 100kg Release date: 2019/08/08
Product Model: windy

Cefoperazone

Modify Date: 2019-02-19 17:09:05
 
Article illustration
Cefoperazone structure
Article illustration Article illustration Article illustration
Common Name
Cefoperazone
CAS Number
62893-19-0
Molecular Weight
645.667
Density
1.8±0.1 g/cm3
Boiling Point
N/A
Molecular Formula
C25H27N9O8S2
Melting Point
169-171ºC
MSDS
ChineseUSA
Flash Point
N/A

 Use of Cefoperazone

 
Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.Target: AntibacterialCefoperazone is a sterile, semisynthetic, broad-spectrum, parenteral cephalosporin antibiotic for intravenous or intramuscular administration. After intravenous administration of 2 g of Cefoperazone, levels in serum rang from 202μg/mL to 375 μg/mL depending on the period of drug administration. After intramuscular injection of 2 g of Cefoperazone, the mean peak serum level is 111 μg/mL at 1.5 hours. At 12 hours after dosing, mean serum levels are still 2 to 4 μg/mL. Cefoperazone is 90% bound to serum proteins.
  • Properties
  • Spectrum

 Names

Name
cefoperazone
Synonym
More Synonyms

 Cefoperazone Biological Activity

Description
Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.Target: AntibacterialCefoperazone is a sterile, semisynthetic, broad-spectrum, parenteral cephalosporin antibiotic for intravenous or intramuscular administration. After intravenous administration of 2 g of Cefoperazone, levels in serum rang from 202μg/mL to 375 μg/mL depending on the period of drug administration. After intramuscular injection of 2 g of Cefoperazone, the mean peak serum level is 111 μg/mL at 1.5 hours. At 12 hours after dosing, mean serum levels are still 2 to 4 μg/mL. Cefoperazone is 90% bound to serum proteins.
Related Catalog
Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Infection
References

[1]. Kato, Y., et al., Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of beta-lactam antibiotics. Drug Metab Dispos, 2008. 36(6): p. 1088-96.

[2]. Craig, W.A. and A.U. Gerber, Pharmacokinetics of cefoperazone: a review. Drugs, 1981. 22 Suppl 1: p. 35-45.

 Chemical & Physical Properties

Density
1.8±0.1 g/cm3
Melting Point
169-171ºC
Molecular Formula
C25H27N9O8S2
Molecular Weight
645.667
Exact Mass
645.142395
PSA
270.86000
LogP
1.43
Index of Refraction
1.819

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Since: 2014-12-17
  • Address: Zhengzhou High tech Zone, Henan Province, China
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