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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Transmembrane Transporters>Sodium Channel Inhibitor>5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5 -dimethoxyphenylamide
5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5 -dimethoxyphenylamide
  • 5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5 -dimethoxyphenylamide

5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5 -dimethoxyphenylamide

Price $1
Package 1KG
Min. Order: 1KG
Update Time: 2019-09-06

Product Details

Product Name: 5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5 -dimethoxyphenylamide CAS No.: 944261-79-4
Min. Order: 1KG Purity: 95%~99%
Supply Ability: per week:100kg Release date: 2019/09/06
Mary003
5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5
-dimethoxyphenylamide Basic information
Synonyms:
5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5lt;brgt;-dimethoxyphenylamide;5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-;5-4(-Chlorophenyl)-N-(3,5-diMethoxyphenyl)furan-2-carboxaMide;2-FurancarboxaMide,5-(4-chlorophenyl)-N-(3,5-diMethoxyphenyl)-;[3H]-A-803467;5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5
CAS:
944261-79-4
MF:
C19H16ClNO4
MW:
357.791
EINECS:
 
Product Categories:
Ion Channels;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors;Sodium channel
Mol File:
944261-79-4.mol
Article illustration
 
5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5
-dimethoxyphenylamide Chemical Properties
Melting point 
128-130?C
storage temp. 
Store at +4°C
solubility 
DMSO: >10mg/mL
form 
powder
color 
white to tan
 
Safety Information
Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
MSDS Information
 
 
5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5
-dimethoxyphenylamide Usage And Synthesis
Chemical Properties
White Solid
Uses
A selective NaV1.8 sodium channel blocker, reduces behavioral measures of chronic pain.
Biological Activity
Selective blocker of Na V 1.8 channels (IC 50 values are 8, 2450, 6740, 7340 and 7380 nM for hNa V 1.8, hNa V 1.3, hNa V 1.7, hNa V 1.5 and hNa V 1.2 channels respectively). Shows no significant activity against TRPV1, P2X 2/3 , Ca V 2.2 and KCNQ2/3 channels. Antinociceptive; potently attenuates mechanical allodynia in two models of neuropathic pain following i.p. administration.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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