MC1568
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Update Time: | 2019-09-06 |
Product Details
| Product Name: MC1568 | CAS No.: 852475-26-4 |
| Min. Order: 1KG | Purity: 95%~99% |
| Supply Ability: per week:100kg | Release date: 2019/09/06 |
Mary004
Tag:MC1568(852475-26-4) Related Product InformationTacedinaline Mocetinostat (MGCD0103) Vorinostat Belinostat (PXD101) Entinostat Givinostat (ITF2357)
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MC1568 Basic information
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Product Name:
MC1568
Synonyms:
(E)-3-[4-[(E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl]-1-methylpyrrol-2-yl]-N-hydroxyprop-2-enamide;3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-Methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenaMide;(E)-3-(4-((E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide;3-[4-[3-(3-Fluorophenyl)-3-oxo-1-propenyl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide MC1568;MC 1568 3-[4-[3-(3-Fluorophenyl)-3-oxo-1-propenyl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide;(E)-3-(5-((E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide;3-[5-(3-(3-Fluorophenyl)-3-oxopropen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide;MC 1568, >=98%
CAS:
852475-26-4
MF:
C17H15FN2O3
MW:
314.3110032
EINECS:
Product Categories:
Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Selective inhibitor of class II (IIa) histone deacetylase (HDAC).;API;Inhibitor;Aromatics
Mol File:
852475-26-4.mol
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MC1568 Chemical Properties
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storage temp.
2-8°C
solubility
DMSO: ≥10mg/mL
form
powder
color
orange
InChIKey
QRDAPCMJAOQZSU-KQQUZDAGSA-N
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Safety Information
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Hazard Codes
Xn,Xi
Risk Statements
22-36
Safety Statements
26
WGK Germany
3
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MSDS Information
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MC1568 Usage And Synthesis
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Uses
A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex.
Uses
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of class IIa HDACs, with greater than 170-fold selectivity over class I HDACs, including HDAC1. It has been used in cells (1-10 μM) and in mice to elucidate the roles of class IIa HDACs in cell proliferation and differentiation, apoptosis, myogenesis, adipogenesis, and fibrosis.[Cayman Chemical]
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MC1568 Preparation Products And Raw materials
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com