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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Novobiocin
Novobiocin
  • Novobiocin
  • Novobiocin
  • Novobiocin
  • Novobiocin
  • Novobiocin

Novobiocin

Price $1
Package 1g
Min. Order: 1g
Update Time: 2019-12-26

Product Details

Product Name: Novobiocin CAS No.: 303-81-1
EC-No.: 206-146-3 Min. Order: 1g
Purity: ≥98% Supply Ability: g/kg/Ton
Release date: 2019/12/26
Delivery Time: Prompt Packaging: Bottle/Durm/Bag
Transportation: By air/Bay Sea/Express

Heidi 0712

Email:heidi@coreychem.com

Novobiocin Basic information
Product Name:
Novobiocin
Synonyms:
NOVOBIOCIN;cathocin;cathomycin;crystallinicacid;-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2h-1-benzopyran-3-yl)-4-hydroxy-;inamycin;novo-r;pa93
CAS:
303-81-1
MF:
C31H36N2O11
MW:
612.628
EINECS:
206-146-3
Product Categories:
 
Mol File:
303-81-1.mol
Article illustration
 
Novobiocin Chemical Properties
Melting point 
170-172 °C
alpha 
D24 -63.0° (c = 1 in ethanol)
Boiling point 
657.29°C (rough estimate)
density 
1.3448
refractive index 
1.5800 (estimate)
pka
pKa1 4.3; pKa2 9.1(at 25℃)
 
Safety Information
WGK Germany 
3
HS Code 
2941906000
MSDS Information
 
 
Novobiocin Usage And Synthesis
Chemical Properties
A light-yellow to white antibiotic produced by Streptomyces niveus. Available as calcium and sodium salts.
Uses
Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.
Uses
Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive antibiotic activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.
Definition
ChEBI: A coumarin-derived antibiotic obtained from Streptomyces niveus.
Brand name
Albamycin.
World Health Organization (WHO)
Novobiocin, an antibiotic with a narrow spectrum of activity, was introduced in 1956. Its use was subsequently associated with serious adverse effects including blood dyscrasias. In view of its toxicity there are no current valid indications for its use. Although preparations containing novobiocin may remain available in some countries it has largely lapsed into disuse.
Hazard
May have damaging side effects.
Veterinary Drugs and Treatments
Novobiocin is approved as a single agent and in combination with penicillin G for use in dry dairy cattle as a mastitis tube. Novobiocin is available in combination with tetracycline and prednisolone for oral use in dogs.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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