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Postion:Product Catalog >API>Hormones and the Endocrine System>Pancreatic hormone and blood sugar regulation>Acarbose
Acarbose
  • Acarbose

Acarbose NEW

Price $50
Package 200mg
Supply Ability: 10g
Update Time: 2025-05-02

Product Details

Product Name: Acarbose CAS No.: 56180-94-0
Purity: 99.69% Supply Ability: 10g
Release date: 2025/05/02

Product Introduction

Bioactivity

NameAcarbose
DescriptionAcarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity.
Cell ResearchCell viability is determined using the MTT assay. Cells are seeded in 24-well culture plates at a density of 2×104 cells/well, incubated for 48 h, treated with acarbose at varying concentrations (0.5, 1.0, 2.0, 3.0, and 5.0 μM) for 24 h; or pre-treated with TNF-α (20 ng/mL) for either 24 h or 48 h to evaluate the dose-dependent effects of acarbose on VSMC growth and viability, cultured with 0.5 mg/mL MTT at 37°C in a humidified atmosphere of 5% CO2 for another 4 h, and solubilized with isopropanol. The viable cell number varies directly with the concentration of formazan product measured spectrophotometrically at 563 nm.
In vitroAcarbose binds to and inhibits α-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. In addition, acarbose inhibits pancreatic α-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines.
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (77.45 mM), Sonication is recommended.
H2O : 64.5 mg/mL (99.91 mM), Sonication is recommended.
Keywordsα-glucosidase | oral | mellitus | insulin | Inhibitor | inhibit | Glucosidase | BAY g-5421 | BAY g5421 | antihyperglycemic | anti-diabetes | Acarbose
Inhibitors Relatedα-Glucosidase-IN-23 | 1-Deoxynojirimycin | Conduritol B epoxide | NCGC00092410 | Voglibose | Pinoresinol diglucoside | N-Caffeoyl O-methyltyramine | Rebaudioside A | (E)-3-(4-Methoxyphenyl)acrylic acid | Naringinase | IHVR-17028 | 3-Butylidenephthalide
Related Compound LibrariesAnti-Tumor Natural Product Library | Bioactive Compound Library | Kinase Inhibitor Library | Saccharide and Glycoside Natural Product Library | Drug Repurposing Compound Library | Natural Product Library | Microbial Natural Product Library | Inhibitor Library | Natural Product Library for HTS | FDA-Approved Kinase Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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