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Postion:Product Catalog >Apicidin
Apicidin
  • Apicidin

Apicidin NEW

Price $299
Package 1mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Apicidin CAS No.: 183506-66-3
Purity: 99.93% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameApicidin
DescriptionApicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic and antiproliferative activity. It attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, making it a valuable tool for leukemia research.
In vitroApicidin (0.1-10 μM, 24 h) inhibits the viability of AT-84 cells in a dose-dependent manner, with concentrations ≥1 μM leading to a significant decrease in viability[1].
In vivoIn the mouse tumor model, at the end of 14 days, Apicidin (5 mg/kg, intraperitoneal injection, once daily) significantly inhibited tumor growth by up to 46% compared to the control group[1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 10 mg/mL (16.03 mM), Sonication is recommended.
KeywordsOSI-2040 | OSI2040 | HDAC | Autophagy | Apoptosis | Apicidin
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Guanidine hydrochloride | Hydroxychloroquine | 2-Amino-2-methyl-1-propanol | Doxycycline | Manganese chloride (tetrahydrate) | Fenpyroximate | Formamide | Paeonol | Alginic acid

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
2026-04-20

TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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