Saikogenin D NEW
| Price | $239 |
| Package | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Saikogenin D | CAS No.: 5573-16-0 |
| Purity: 99.99% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Saikogenin D |
| Description | Saikogenin D possesses dual mechanisms of action including inhibition of A23187-induced PGE2 production without direct cyclooxygenase suppression, and stimulation of intracellular calcium elevation through Ca2+ release from internal stores, while further displaying immunomodulatory properties demonstrated by its ability to attenuate IL-6 production in LPS-stimulated alveolar macrophages from B6 mice more strongly than in BALB mice, highlighting selective regulation of inflammatory responses. |
| In vitro | In C6 rat glioma cells, Saikogenin D (1-20 μM) inhibited calcium ionophore A23187-induced PGE2 production in a concentration-dependent manner, with an IC50 of 3 μM[1]. In C6 rat glioma cells, Saikogenin D (10-100 μM) increased intracellular calcium concentration ([Ca2?]i) in a concentration-dependent manner regardless of the presence of extracellular calcium ions, with an EC50 of 35 μM[1]. |
| Storage | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : ≥ 80 mg/mL, Sonication is recommeded. |
| Keywords | Saikogenin D | ProstaglandinReceptor | Prostaglandin Receptor | PGE | ILReceptor | IL Receptor | CalciumChannel | Calcium Channel |
| Inhibitors Related | Quadrol | 2,4,6-Tri-tert-butylphenol | Uridine 5'-monophosphate disodium salt | Chlorocresol | L-Ascorbic acid | 1,8-Cineole | Chenodeoxycholic acid | L-Ascorbic acid sodium salt | 2-Nitrobenzoic acid | Diallyl disulfide | Magnesium Chloride Hexahydrate | Magnesium sulfate |
| Related Compound Libraries | Terpene Natural Product Library | Bioactive Compound Library | Calcium Channel Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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