Product Details
| Product Name:
AZD8309 |
CAS No.:
333742-48-6 |
| Purity:
98.64% |
Supply Ability:
10g |
| Release date:
2026/05/06 |
Product Introduction
Bioactivity
| Name | AZD8309 |
| Description | AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the pancreas.AZD8309 can be used to study a range of inflammatory diseases. |
| In vivo | Oral dministration of AZD8309 (50 mg/kg) reduced neutrophil migration and pancreatic protease activation in experimental pancreatitis in mice.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 65 mg/mL (169.09 mM), Sonication is recommended.
|
| Keywords | MPO | GlutathionePeroxidase | Glutathione Peroxidase | CXCR2 | AZD8309 |
| Inhibitors Related | Tannic acid | Artemotil | 4-Aminosalicylic acid | Kynurenic acid | 2-Acetamidophenol | PF-1355 | Soquelitinib | Sodium 2-mercaptoethanesulfonate | 5-Aminosalicylic Acid | Probucol | Nicotinamide N-oxide | Cefdinir |
| Related Compound Libraries | Bioactive Compound Library | Cytokine Inhibitor Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Chemokine Inhibitor Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Price |
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States