Ilomastat NEW
| Price | $41 | $59 | $96 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-05 |
Product Details
| Product Name: Ilomastat | CAS No.: 142880-36-2 |
| Purity: 98.18% | Supply Ability: 10g |
| Release date: 2026/06/05 |
Product Introduction
Bioactivity
| Name | Ilomastat |
| Description | Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor. |
| Kinase Assay | Collagenase assay uses the synthetic thiol ester substrate Ac-Pro-Leu-Gly-SCH(i-Bu)CO-Leu-Gly-OEt at pH 6.5. The collagenase concentration is 1-2 nM, and the substrate concentrations are from 0.1 to 0.7 nM. Km?is found to vary between 1.5 and 4 mM. |
| In vivo | Topical application of GM6001 (400 μg/ml) prevents corneal ulceration after severe alkali injury. [3] In rabbit model after stenting, GM6001 significantly inhibits intimal hyperplasia and intimalcollagen content, and it increases lumen area in stented arteries without effects on proliferation rates. [4] |
| Storage | Keep away from moisture,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 83.32 mg/mL (214.49 mM) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (8.5 mM), Sonication is recommended. |
| Keywords | MMP-9 | MMP-8 | MMP-7 | MMP-26 | MMP-2 | MMP-12 | MMP-1 | MMP | Matrix metalloproteinases | Inhibitor | inhibit | Ilomastat | GM-6001 | GM 6001 |
| Inhibitors Related | Rhamnose monohydrate | Doxycycline (hyclate) | Chondroitin sulfate | Astragaloside IV | Doxycycline | Edaravone | Glucosamine | Anethole | Meloxicam | Chloramphenicol | Propoxur | Methylchloroisothiazolinone/Methylisothiazolinone Mixture |
| Related Compound Libraries | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Protease Inhibitor Library | Angiogenesis related Compound Library | Inhibitor Library | Anti-Fibrosis Compound Library | NO PAINS Compound Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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