B220 NEW
| Price | $178 | $447 | $592 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-15 |
Product Details
| Product Name: B220 | CAS No.: 112228-65-6 |
| Purity: 99.90% | Supply Ability: 10g |
| Release date: 2026/05/15 |
Product Introduction
Bioactivity
| Name | B220 |
| Description | B220 is an indoloquinoline antiviral agent that inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV). B220 exhibits antiviral and immunomodulatory activity. |
| In vitro | Methods: Add 3 μM B220 to HCT116 colorectal cancer cells and treat for 6, 12, 24, or 48 hours. Detect cell cycle progression via PI staining and flow cytometry. Results: 6–24 hours: Cells significantly accumulated in the G2/M phase. 48 hours: Sub-G1 phase cells (apoptosis peak) significantly increased. [1] Methods: Human neutrophils were pretreated with B220 (5, 10 μg/mL) for 5 min, then stimulated with serum-conditioned yeast particles (PMA) (5×10?? M). Chemiluminescence signals were continuously recorded post-stimulation (approx. 30–60 min) using luminol-enhanced chemiluminescence (containing SOD and catalase to detect intracellular ROS). Results: B220 dose-dependently inhibited PMA- and calyptra-induced intracellular ROS production. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 9 mg/mL (28.26 mM), Sonication is recommended. |
| Keywords | HSV-1 | B-220 | B220 | B 220 |
| Inhibitors Related | Rifampicin | Phenytoin sodium | Levofloxacin hydrochloride | L-Lysine | L-Lysine hydrochloride | Oxyresveratrol | Ofloxacin | Vidarabine | Acyclovir sodium | Acyclovir | Thymidine | Danthron |
| Related Compound Libraries | Bioactive Compound Library | ReFRAME Related Library | Anti-Viral Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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TargetMol Chemicals Inc.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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