Isofraxidin NEW
| Price | $38 | $71 | $106 |
| Package | 10mg | 25mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-19 |
Product Details
| Product Name: Isofraxidin | CAS No.: 486-21-5 |
| Purity: 99.74% | Supply Ability: 10g |
| Release date: 2026/05/19 |
Product Introduction
Bioactivity
| Name | Isofraxidin |
| Description | 1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 40 mg/mL (180.03 mM), Sonication is recommended. Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (9 mM), Sonication is recommended. |
| Keywords | Toll-like Receptor (TLR) | TLR4 | TLR | p38MAPK | p38 MAPK | p38 | MMP-7 | MMP | MD-2 | Matrix metalloproteinases | Isofraxidin | invasion | iNOS | Inhibitor | inhibit | hepatoma | ERK1/2 | ERK | Cyclooxygenase | COX-2 | COX | cell |
| Inhibitors Related | Urea | Rhamnose monohydrate | Gum arabic | Acetaminophen | Hydroxychloroquine | Fumaric acid | Benzyl alcohol | Doxycycline | Glucosamine | D-Psicose | Trometamol | Gluconate Calcium |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Inhibitor Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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