BAY-298 NEW
| Price | $3018 |
| Package | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: BAY-298 | CAS No.: 2471978-97-7 |
| Supply Ability: 10g | Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | BAY-298 |
| Description | BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1]. |
| In vivo | BAY-298 administered orally at dosages ranging from 4.5 to 72 mg/kg/day over a period of 8 days, leads to a dose-dependent reduction in serum estradiol levels in proestrus in intact female rats. Additionally, when administered to female and male Wistar rats either intravenously (iv) at a dosage of 0.5 mg/kg or orally (po) at 2 mg/kg, BAY-298 exhibits half-lives of 31 hours and 33 hours, respectively, for iv and po routes. The maximum serum concentrations (Cmax) achieved are 0.28 kg/L for iv and 0.066 kg/L for po administration. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | rLH | hLH | cLH | BAY-298 | BAY298 | BAY 298 |
| Inhibitors Related | BAY-784 | Fluorogestone acetate | Degarelix acetate(214766-78-6 free base) | Relugolix | BAY 1214784 | Opigolix | Goserelin acetate | Linzagolix choline | Alarelin Acetate | Linzagolix | Cetrorelix diacetate | AG 045572 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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