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Postion:Product Catalog >Bemesetron
Bemesetron
  • Bemesetron

Bemesetron NEW

Price $30 $38 Get Latest Price
Package 10mg 25mg 50mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Bemesetron CAS No.: 40796-97-2
Purity: 99.77% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameBemesetron
DescriptionBemesetron (MDL 72222) is a selective 5-HT3 antagonist (IC50 = 0.33 nM) that exhibits neuroprotective effects.
In vitroIn primary cortical neuronal cells, Bemesetron (1 μM) significantly blocks the H2O2-induced increase of caspase-3 immunoreactivity. Bemesetron (0.01, 0.1 and 1 μM) and Y25130 (0.05, 0.5 and 5 μM) concentration-dependently reduce the H2O2-induced decrease showing inhibition of 74.9 and 79.0% with 1 μM and 5 μM, respectively[2].
In vivoIn male adult albino mice, Bemesetron (1 mg/kg; i.p.) causes a significant reduction of catalepsy, while Bemesetron (10 mg/kg; i.p.) significantly potentiates the phenomenon. The maximum inhibition of catalepsy (about 75%) occurs at 120 min, and the maximum potentiation (about 4.5-times the control value) occurs at 60 min after Haloperidol[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 2 mg/mL (6.37 mM), Sonication is recommended.
KeywordsMDL-72222 | MDL72222 | Bemesetron | 5HTReceptor | 5-HT3 Receptor | 5-HT3 | 5HT Receptor
Inhibitors RelatedAlverine citrate | Sevoflurane | Dapoxetine hydrochloride | Cefaclor monohydrate | Clozapine N-Oxide | 1,8-Cineole | Dopamine hydrochloride | Cloperastine hydrochloride | Mianserin hydrochloride | Trazodone hydrochloride | Cinchonidine | Doxepin hydrochloride
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Angiogenesis related Compound Library | Neuroprotective Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Serotonin Receptor-Targeted Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
VIP4Y
TargetMol Chemicals Inc.
2026-04-22

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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