Berberine chloride NEW
| Price | $30 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-07-15 |
Product Details
| Product Name: Berberine chloride | CAS No.: 633-65-8 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2026/07/15 |
Product Introduction
Bioactivity
| Name | Berberine chloride |
| Description | Berberine chloride (Natural Yellow 18) is an alkaloid derived from Hydrastis canadensis L. of the Berberidaceae family, serving as a commonly used intestinal antibacterial agent. Berberine chloride exhibits biological activities including anti-inflammatory, hypoglycemic, lipid-regulating, antitumor, and cardiovascular protective effects. Berberine chloride can be utilized in research on chronic diseases and tumors. |
| In vitro | Methods: Copper complexes (0–100 μM), berberine chloride (0–100 μM), and a combination treatment (copper complexes (0–100 μM) + BBC (50 μM)) were added to MDA-MB-231 VIM RFP (triple-negative breast cancer cells) and MCF-10A (normal human mammary epithelial cells). Incubation time: 24, 48, 72 h; cell viability was assessed using the CCK-8 assay. Results: Berberine chloride significantly inhibited cell growth, and combination therapy significantly enhanced cytotoxicity against cancer cells. [1] Methods: LoVo cells were treated with 40 μM berberine chloride for 24 h, and cell cycle distribution was analyzed by flow cytometry. Results: Berberine chloride induced G?/M phase arrest in LoVo cells. [2] |
| In vivo | Methods: Using a LoVo cell xenograft model in nude mice, Berberine chloride was administered orally at doses of 10, 30, and 50 mg/kg for 10 consecutive days, and the tumor suppression rate was calculated. Results: The tumor suppression rate for 50 mg/kg Berberine chloride reached 45.3%, with no significant toxicity observed in mouse body weight or spleen.[2] |
| Storage | Keep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 21.00 mg/mL (56.48 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) H2O : < 1 mg/mL (insoluble or slightly soluble) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1.00 mg/mL (2.69 mM), Sonication is recommended. |
| Keywords | Topoisomerase | ReactiveOxygenSpecies | Reactive Oxygen Species | Natural Yellow-18 | Natural Yellow18 | Inhibitor | inhibit | Berberine Hydrochloride | Berberine Chloride | Berberine | Bacterial | Autophagy | Antibiotic |
| Inhibitors Related | Sucrose | Neomycin sulfate | Aceglutamide | Hemin | D(+)-Raffinose pentahydrate | Ethyl linoleate | Malic acid | Glycerol | Thymidine | Dimethyl sulfoxide | Gluconate Calcium | Sodium bicarbonate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Alkaloid Natural Product Library | Drug Repurposing Compound Library | Natural Product Library | Anti-Viral Compound Library | Antiparasitic Natural Product Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bitter Compound library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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