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Postion:Product Catalog >BMT-090605
BMT-090605
  • BMT-090605

BMT-090605 NEW

Price $2120 $2780 $3700
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: BMT-090605 CAS No.: 1551403-51-0
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameBMT-090605
DescriptionBMT-090605 is a potent, selective AAK1 inhibitor with an IC50 of 0.6 nM, and inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 also exhibits antinociceptive activity.
In vitroBMT-090605 shows a cellular IC50 of 0.63 ±0.39 nM for AAK1[1].
In vivoBMT-090605 (0.3-3 μg/rat; intrathecally at lumbar level L5/L6) causes antinociception by inhibiting AAK1 in the spinal cord[1]. Exposure measurements from this study indicated that brain and plasma levels of BMT-090605 were <4 nM, whereas measurable levels (90–317 nM) were observed in lumbar spinal cord[1]. The high dose of BMT-090605 (3 μg/rat) showed efficacy comparable to intrathecal clonidine (3 μg/rat).
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsBMT-090605 | BMT090605 | BMT 090605
Inhibitors RelatedCulmerciclib | Fasudil | Bicyclol | Piceatannol | Chymotrypsin | Fasudil hydrochloride | Camostat mesylate | 6-(Dimethylamino)purine | FOY 251 | SGC-AAK1-1 | Benzamidine hydrochloride | Cetraxate hydrochloride

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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