BMT-145027 NEW
| Price | $34 | $56 | $94 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-08 |
Product Details
| Product Name: BMT-145027 | CAS No.: 2018282-44-3 |
| Purity: 99.62% | Supply Ability: 10g |
| Release date: 2026/06/08 |
Product Introduction
Bioactivity
| Name | BMT-145027 |
| Description | BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM). |
| In vitro | BMT-145027 lacks inherent mGluR5 agonist activity when tested at concentrations up to 16 μM. BMT-145027 exhibits high MsLM stability (85% remaining) and a modest decrease in planarity (Fsp3 = 0.17)[1]. |
| In vivo | BMT-145027 (30 mg/kg) leads to a significant increase in time spent with the novel object, with an apparent trend in novel object preference at 10 mg/kg. Satellite animals(BMT-145027: 30 mg/kg) indicates a total plasma concentration of 2800 nM[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2 mg/mL (4.56 mM), Sonication and heating are recommended. |
| Keywords | mGluR5 | mGluR | Metabotropic glutamate receptors | Inhibitor | inhibit | BMT-145027 | BMT145027 | BMT 145027 |
| Inhibitors Related | IDRA-21 | Urethane | Decanoic Acid | Kynurenic acid | DCB | L-Cysteic acid monohydrate | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Memantine hydrochloride | O-Phospho-L-serine |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Glutamine Metabolism Compound Library | Neurotransmitter Receptor Compound Library | Neuroprotective Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Fluorochemical Library | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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