C75 NEW
| Price | $41 | $59 | $98 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: C75 | CAS No.: 218137-86-1 |
| Purity: 98.84% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | C75 |
| Description | C75 is a fatty acid synthase (FASN) inhibitor (IC50 = 35 μM in PC3 cells) with cell permeability and the ability to activate CPT1A. This compound possesses antitumor activity and is commonly used in cancer-related experimental research. |
| In vitro | Methods: The in vitro activity of C75 was validated using HeLa and CaSki cells. Cells were pretreated with 50 μM C75 for 1 hour, followed by wound healing, Transwell migration/invasion, and tube formation assays. Results: C75 significantly inhibited the migration, invasion, and lymphangiogenesis abilities of cervical cancer cells. [1] |
| In vivo | Methods: BALB/c nude mice were used to establish a cervical cancer lymph node metastasis model, with HeLa or CaSki cells inoculated into the footpad. C75 was administered via intraperitoneal injection at a dose of 10 mg/kg every other day for 2 weeks, with vehicle as control. Results: C75 treatment significantly suppressed popliteal lymph node volume and metastasis rate, and reduced lymphatic vessel density at the tumor site. [1] Methods: A 4T1 breast cancer-bearing Balb/c mouse model was used, with C75 administered via intraperitoneal injection at a dose of 10 mg/kg every 3 days for 17 consecutive days. Results: C75 monotherapy mildly inhibited tumor growth, while combination with CYH33 synergistically enhanced antitumor efficacy, increased FFA levels in tumor tissue, promoted CD8? T cell infiltration, and reduced M2 macrophages. [2] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 0.5% CMC-Na : 5 mg/mL (19.66 mM), Suspension. DMSO : 75.6 mg/mL (297.26 mM), Sonication is recommended. |
| Keywords | PC3 cell | FattyAcidSynthase | Fatty Acid Synthase (FASN) | Fatty Acid Synthase | C75 | C 75 |
| Inhibitors Related | HpFabZ Inhibitor 1 | 2-Octanone | Betulin | Malic enzyme inhibitor ME1 | Maltitol | Pyrazinamide | A-769662 | trans-Chalcone | Orlistat | L-Carnitine | Pseudoprotodioscin | Lycorine |
| Related Compound Libraries | Anti-Obesity Compound Library | Bioactive Compound Library Plus | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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