Cetrimonium bromide NEW
| Price | $30 | $39 | $55 |
| Package | 50mg | 100mg | 200mg |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Cetrimonium bromide | CAS No.: 57-09-0 |
| Purity: 98% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Cetrimonium bromide |
| Description | Cetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide. |
| In vitro | In a FaDu xenograft tumor model established in SCID mice, intraperitoneal administration of 5 mg/kg Cetrimonium Bromide daily for five consecutive days moderately inhibited tumor growth as compared to the vehicle treatment arm. Additionally, 5 μM of Cetrimonium Bromide effectively prevented tumor formation in FaDu cells within SCID mice. |
| In vivo | Cetrimonium Bromide exhibits a dose-dependent and radiation potentiating interaction that inhibits the clonogenic survival of FaDu cells. It induces nuclear pyknosis and bubbling in FaDu cells, consistent with the morphology of apoptotic nuclei, which is not observed in CTAB-treated GM05757 cells. Additionally, it reproducibly suppresses ATPase activity in FaDu cells, achieving approximately 90% inhibition at 50 μM. Cetrimonium Bromide reduces the cell viability in a variety of cell lines including FaDu, C666-1, UTSCC-8A, UTSCC-42A, MRC5, and GM05757 fibroblasts, with respective EC50 values of 2 μM, 3.8 μM, 3.5 μM, 4.2 μM, 11 μM, and 18 μM. It also diminishes the cell viability of A549 lung and MCF7 breast cancer cells with EC50 values of 17 μM and 12 μM, respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mg/mL (27.4 mM), Sonication is recommended. Ethanol : 93 mg/mL (255.17 mM), Sonication is recommended. H2O : 100 mg/mL (274.38 mM), Sonication is recommended. |
| Keywords | Inhibitor | inhibit | Hexadecyltrimethylammonium | Cetyltrimethylammonium | Cetrimonium bromide | Cetrimonium Bromide | Cetrimonium | Antibiotic |
| Inhibitors Related | Neomycin sulfate | L-Lactic acid | Ampicillin sodium | Doxycycline (hyclate) | Cefaclor monohydrate | Kanamycin sulfate | Rifaximin | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Sulfachloropyridazine |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Antibiotics Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Cosmetic Ingredient Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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