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Postion:Product Catalog >Chlortalidone Impurity
Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity

Chlortalidone Impurity NEW

Price Get Latest Price
Package 10mg 50mg 100mg
Min. Order: 10mg
Supply Ability: 1000
Update Time: 2025-12-16

Product Details

Product Name: Chlortalidone Impurity CAS No.: 955-16-8
Min. Order: 10mg Purity: 99%+ HPLC
Supply Ability: 1000 Release date: 2025/12/16

Chlortalidone Impurity; 955-16-8

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WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com

  • .

  • Chlortalidone Impurity 3

  • Product Information

  • Product Code: C138003

  • English Name: Chlortalidone Impurity 3

  • English Alias: 5-phenylisobenzofuran-1,3-dione

  • CAS No.:955-16-8

  • Molecular Formula: C??H?O?

  • Molecular Weight: 224.21

  • Advantages

  • Purity Assurance: HPLC ≥99.5%, confirmed by IR and melting point analysis.

  • Stability: Shelf life of 36 months at room temperature, with <0.1% degradation in ethyl acetate.

  • Regulatory Compliance: Meets ICH Q3A for organic impurities in diuretics.

  • Applications

  • Residual Impurity Control: Detects benzofuranone in Chlortalidone via GC-MS.

  • Process Optimization: Monitors decarboxylation side reactions during synthesis.

  • Method Validation: Validates GC methods for volatile impurities.

  • Background Description

  • This impurity originates from thermal degradation or cyclization of benzoic acid intermediates. It requires control due to potential genotoxicity concerns.
  • Research Status

  • Detection: GC-MS with DB-5 column; LOD: 1 ppm.

  • Formation: Induced by high-temperature reaction steps; reducing reaction temperature lowers content by 80%.

  • Toxicity: Ames test shows no mutagenicity; further genotoxicity studies ongoing.

NOTE!

We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com


NEW IN STOCK!

The Molcoo Laboratory added drug impurity reference standards, including Baricitinib, Piperazine, Benzylpenicillin, Tranilast and multiple N-Nitroso drug impurities! Now available for immediate delivery! 


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