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Postion:Product Catalog >Chlortalidone Impurity
Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity
  • Chlortalidone Impurity

Chlortalidone Impurity NEW

Price Get Latest Price
Package 10mg 50mg 100mg
Min. Order: 10mg
Supply Ability: 1000
Update Time: 2025-12-16

Product Details

Product Name: Chlortalidone Impurity CAS No.: 13450-37-8
Min. Order: 10mg Purity: 99%+ HPLC
Supply Ability: 1000 Release date: 2025/12/16

Chlortalidone Impurity; 13450-37-8

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WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com


  • Chlortalidone Impurity 2

  • Product Information

  • Product Code: C138002

  • English Name: Chlortalidone Impurity 2

  • English Alias: 2-(3-chlorobenzoyl)benzoic acid

  • CAS No.:13450-37-8

  • Molecular Formula: C??H?ClO?

  • Molecular Weight: 260.67

  • Advantages

  • High Purity & Structural Confirmation: HPLC ≥99.0%, validated by NMR and HRMS.

  • Stability: Stable for 24 months at -20℃, with <0.3% degradation in methanol.

  • Regulatory Compliance: Meets EP/USP standards for diuretic impurity control.

  • Applications

  • Impurity Detection: Quantifies Impurity 2 in Chlortalidone formulations via LC-MS.

  • Synthesis Monitoring: Tracks 3-chlorobenzoyl residue during ring closure reactions.

  • Method Validation: Supports specificity testing for chromatographic methods.

  • Background Description

  • This impurity forms from isomeric chlorobenzoyl reagents in Chlortalidone synthesis. Controlling positional isomers is critical for drug quality.
  • Research Status

  • Detection: HPLC with C18 column (5μm) and gradient elution; LOD: 0.05 μg/mL.

  • Formation Mechanism: Results from ortho/meta chlorination selectivity; using catalyzed chlorination reduces meta-isomer by 65%.

  • Safety Evaluation: Acute toxicity tests show no adverse effects; chronic studies in progress.

NOTE!

We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com


NEW IN STOCK!

The Molcoo Laboratory added drug impurity reference standards, including Baricitinib, Piperazine, Benzylpenicillin, Tranilast and multiple N-Nitroso drug impurities! Now available for immediate delivery! 


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