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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>CTS-1027
CTS-1027
  • CTS-1027

CTS-1027 NEW

Price $97
Package 2mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: CTS-1027 CAS No.: 193022-04-7
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameCTS-1027
DescriptionCTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.
In vivoCTS-1027 improves overall animal survival following 14 days of BDL in mice [1]. CTS-1027 effectively reduces features of cholestatic liver injury, the hepatocyte apoptosis, and markers of hepatic fibrogenesis in the BDL mouse. The terminal plasma concentration of RS-130830 is 311 nM, in male animals treated for 8 weeks. RS-130830(8 weeks; male mice ) treatment causes an 89% increase in plasma triglyceride concentration. But there is no corresponding effect in female mice treated for 12 weeks. The plaque lipid content of animals receiving RS-130830 is increased by 81% at 12 weeks, and increased by 41% at 16 weeks [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (7.75 mM), Sonication is recommended.
DMSO : 100 mg/mL (234.81 mM), Sonication is recommended.
KeywordsRS-130830 | RS130830 | MMP8 | MMP3 | MMP2 | MMP14 | MMP13 | MMP12 | CTS-1027 | CTS1027 | CTS 1027
Inhibitors RelatedRhamnose monohydrate | Doxycycline (hyclate) | Chondroitin sulfate | Astragaloside IV | Doxycycline | Edaravone | Glucosamine | Anethole | Meloxicam | Chloramphenicol | Propoxur | Methylchloroisothiazolinone/Methylisothiazolinone Mixture

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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