Product Details
| Product Name:
DFHO |
CAS No.:
1420815-34-4 |
| Purity:
99.80% |
Supply Ability:
10g |
| Release date:
2026/04/22 |
Product Introduction
Bioactivity
| Name | DFHO |
| Description | DFHO is a Corn homologous ligand that fluoresces yellow upon excitation and is used to image RNA in living cells. |
| Cell Research | I. RNA imaging
1. Aptamer preparation: Corn fluorescent aptamer is combined with target RNA molecules.
2. DFHO binding: DFHO is added to the RNA-aptamer complex. Through its high affinity and fluorescence properties, DFHO will bind to the aptamer and convert to a fluorescent state.
3. Imaging: Through fluorescence microscopy, the fluorescence of DFHO can help locate and quantify the presence of RNA molecules.
4. Optimization: The concentration of DFHO, incubation time, temperature and other conditions can be adjusted to optimize the intensity and stability of the signal.
II. RNA molecular dynamics study
1. Cell treatment: DFHO (1-20uM) and Corn fluorescent aptamer are added to cell culture to label specific RNA in cells.
2. Imaging analysis: Combined with real-time fluorescence microscopy to monitor the changes of RNA in cells, analyze the distribution, transcription and synthesis dynamics of RNA.
III. Gene expression study
1. RNA labeling: Use Corn fluorescent aptamer to label RNA molecules of specific genes.
2. DFHO labeling: Use DFHO to convert RNA signals into visible fluorescent forms.
3. Analysis: Analyze RNA expression at different time points and conditions through fluorescent imaging.
The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (284.48 mM), Sonication is recommended.
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| Keywords | DFHO |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States