Diprotin A TFA NEW
| Price | $49 |
| Package | 2mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Diprotin A TFA | CAS No.: 209248-71-5 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Diprotin A TFA |
| Description | Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV). |
| In vitro | Diprotin A can increase the phosphorylation of Src and vascular endothelial cadherin (VE-cadherin) in human endothelial cells and destroy the connection between endothelial cells, which can be blocked by CXCR4 (SDF-1α receptor) or Src inhibitor Weaken. |
| In vivo | Diprotin A collectively induces vascular leakage by increasing the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway. In the model of retinopathy of prematurity, Diprotin A will not only increase retinal blood vessels, but also increase leakage. In addition, in the murine model of diabetic retinopathy, bupstatin A increases the phosphorylation of Src and VE-cadherin and aggravates retinal vascular leakage. |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 77.5 mg/mL (170.15 mM), Sonication is recommended. |
| Keywords | Ile-Pro-Pro | Diprotin A TFA |
| Inhibitors Related | Tripterin | Sitagliptin | Teneligliptin hydrobromide | Sitagliptin phosphate monohydrate | 10-Undecenoic acid | Anagliptin | Aprotinin | 10-Undecenoic acid zinc salt | Vildagliptin | Sitagliptin phosphate | Alloxan monohydrate | 4'-Hydroxychalcone |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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