Ezetimibe ketone NEW
| Price | $35 |
| Package | 2mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Ezetimibe ketone | CAS No.: 191330-56-0 |
| Purity: 99.32% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Ezetimibe ketone |
| Description | Ezetimibe ketone (EZM-K) is a metabolite of Ezetimibe with antioxidant activity, alleviating H2O2-induced apoptosis and reactive oxygen species (ROS) in NRK-52E cells, upregulating Nrf2 and HO-1 levels. |
| In vitro | Ezetimibe ketone alleviates H2O2-induced apoptosis and reactive oxygen species (ROS) production in NRK-52E cells, and upregulates Nrf2 and HO-1 levels. [1] |
| In vivo | In rat RIRI models, pretreatment with Ezetimibe ketone activated Nrf2/HO-1 signaling pathway, inhibited renal tubule injury and inflammation, and improved renal function. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.91 mM), Sonication is recommended. DMSO : 80 mg/mL (196.36 mM), Sonication is recommended. |
| Keywords | Nrf2 | NPC1L1 | Ezetimibe ketone |
| Inhibitors Related | Ethoxyquin | Kaolin | Stavudine | Aceglutamide | Allopurinol | Hemin | Guanidine hydrochloride | Hydroxychloroquine | Ethyl linoleate | Paeonol | Naringin | Alginic acid |
| Related Compound Libraries | Ferroptosis Compound Library | Bioactive Compound Library | Antioxidant Compound Library | Mitochondrial Protection Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
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