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Postion:Product Catalog >GNE 220
GNE 220
  • GNE 220

GNE 220 NEW

Price $1960 $2670 $3390
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-22

Product Details

Product Name: GNE 220 CAS No.: 1199590-75-4
Supply Ability: 10g Release date: 2026/05/22

Product Introduction

Bioactivity

NameGNE 220
DescriptionGNE-220 is a potent and selective inhibitor of MAP4K4, with an IC50 of 7 nM.
In vitroGNE-220 alters human umbilical vein endothelial cells (HUVEC) sprout morphology.?GNE-220 also reduces pERM+ retraction fibres in a dose-dependent manner.?GNE-220 also dose-dependently increased the number of active-INTβ1+ long focal adhesions (FAs).GNE-220 also inhibits a few other kinases with IC50s of 9 nM, 476 nM and 1.1 μM for MINK (MAP4K6), DMPK and KHS1 (MAP4K5), respectively.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsMAP4K6 | MAP4K5 | MAP4K4 | GNE-220 | GNE220 | GNE 220
Inhibitors RelatedSodium lauryl sulfoacetate | Phosphocreatine disodium hydrate | Vemurafenib | SKLB-163 | RV01 | Takinib | NG25 | Phosphocreatine disodium | RMM-46 | Oleanolic Acid | Dehydrocostus Lactone | Sodium new houttuyfonate

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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