Product Details
| Product Name:
GNE 220 |
CAS No.:
1199590-75-4 |
| Supply Ability:
10g |
Release date:
2026/05/21 |
Product Introduction
Bioactivity
| Name | GNE 220 |
| Description | GNE-220 is a potent and selective inhibitor of MAP4K4, with an IC50 of 7 nM. |
| In vitro | GNE-220 alters human umbilical vein endothelial cells (HUVEC) sprout morphology.?GNE-220 also reduces pERM+ retraction fibres in a dose-dependent manner.?GNE-220 also dose-dependently increased the number of active-INTβ1+ long focal adhesions (FAs).GNE-220 also inhibits a few other kinases with IC50s of 9 nM, 476 nM and 1.1 μM for MINK (MAP4K6), DMPK and KHS1 (MAP4K5), respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | MAP4K6 | MAP4K5 | MAP4K4 | GNE-220 | GNE220 | GNE 220 |
| Inhibitors Related | Sodium lauryl sulfoacetate | Phosphocreatine disodium hydrate | Vemurafenib | SKLB-163 | RV01 | Takinib | NG25 | Phosphocreatine disodium | RMM-46 | Oleanolic Acid | Dehydrocostus Lactone | Sodium new houttuyfonate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$10.00
|
VIP6Y
|
RongNa Biotechnology Co.,Ltd
|
2026-07-13 |
|
|
$41.00
|
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-07-14 |
|
|
$3390.00
|
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-05-22 |
|
|
$3400.00
|
VIP2Y
|
TargetMol Chemicals Inc.
|
2025-07-23 |