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Postion:Product Catalog >Analytical Chemistry>Standard>Pharmaceutical Impurity Reference Standards>Hydroxy Itraconazole
Hydroxy Itraconazole
  • Hydroxy Itraconazole

Hydroxy Itraconazole NEW

Price $278 $619 $993
Package 2mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-07-15

Product Details

Product Name: Hydroxy Itraconazole CAS No.: 112559-91-8
Purity: 99.59% Supply Ability: 10g
Release date: 2026/07/15

Product Introduction

Bioactivity

NameHydroxy Itraconazole
DescriptionHydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.
In vitroHydroxy Itraconazole is considered to have antifungal effects in vitro. It contains a triazole ring in its structure and is capable of inhibiting the CYP3A enzyme. [1]
In vivoPlasma concentrations of Hydroxy Itraconazole do not correlate well with ITZ doses, probably because the process of forming Hydroxy Itraconazole is saturated. Factors such as serum albumin and GFR affect the pharmacokinetics of ITZ and Hydroxy Itraconazole. When considering antifungal activity, it is important to look not only at plasma concentrations of ITZ, but also at plasma concentrations of Hydroxy Itraconazole. However, the pharmacokinetics of Hydroxy Itraconazole in immunocompromised patients receiving oral ITZ solutions are similar to those of ITZ. Therefore, since plasma concentrations of ITZ and Hydroxy Itraconazole are highly correlated, determining plasma concentrations of both should be sufficient from a clinical standpoint. [1]
StorageStore at low temperature,Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 80 mg/mL (110.86 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.57 mM), Sonication is recommended.
KeywordsR63373 | R 63373 | Hydroxyitraconazole | Hydroxy Itraconazole | Antifungal
Inhibitors RelatedNeomycin sulfate | Calcium Propionate | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Benzyl propionate | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate
Related Compound LibrariesBioactive Compound Library | Anti-Fungal Compound Library | Anti-Bacterial Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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