Idoxifene NEW
| Price | $619 | $1070 | $1820 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: Idoxifene | CAS No.: 116057-75-1 |
| Purity: 100.00% | Supply Ability: 10g |
| Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | Idoxifene |
| Description | Idoxifene (CB7432) is a selective and tissue-specific estrogen receptor modulator (SERM) that reduces collagen and malondialdehyde (MDA) levels in rat liver, exhibiting anti-fibrotic effects. |
| In vitro | In vascular smooth muscle cells, Idoxifene inhibits Angiotensin II-induced reactive oxygen species (ROS) production [1]. In cultured activated hepatic stellate cells, Idoxifene dose-dependently inhibits activation and proliferation while time-dependently inducing apoptosis [1]. Idoxifene acts as an estrogen receptor agonist on osteoblasts in bone and exhibits weak agonist activity in human endometrial cells. Idoxifene and estradiol (E2) protect hepatocytes from inflammatory cell damage by inhibiting NF-κB activation [2]. |
| In vivo | Following DMN treatment, rats administered daily intraperitoneal estradiol (0.5 mg/kg) alongside Idoxifene (0.1 and 0.5 mg/kg; oral) for 3 days exhibited dose-dependent reductions in liver collagen and malondialdehyde (MDA) levels, demonstrating antifibrotic effects [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 40 mg/mL (76.42 mM), Sonication is recommended. |
| Keywords | Idoxifene | Estrogen receptor | CB-7432 | CB 7432 |
| Inhibitors Related | Tamoxifen | Estradiol | 2-Ethylhexyl trans-4-methoxycinnamate | Diisopropyl phthalate | Estradiol benzoate | Bisphenol B | Mequinol | Phthalic acid | Chlorothalonil | Ethisterone | Tamoxifen Citrate | Cholesterol |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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