Product Details
| Product Name:
JB062 |
CAS No.:
2417988-00-0 |
| Purity:
99.89% |
Supply Ability:
10g |
| Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | JB062 |
| Description | JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It selectively exhibits cytotoxicity towards human cancer cells without affecting normal cells. The compound is applicable in research fields concerning muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy. |
| In vitro | JB062 (40 μM ; 24 h) inhibited cytoplasmic division in COS-7 cells.[1]
JB062 (COS-7 cells) exhibited cytotoxicity against human cancer cells but showed no cytotoxicity towards normal cells, with an IC50 value of 36 μM.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 22.5 mg/mL (69.59 mM), Sonication is recommended.
|
| Keywords | Myosin |
| Inhibitors Related | Mavacamten | (-)-Blebbistatin | Myosin V-IN-1 | JB002 | Aficamten | ATM-3507 | Myosin-IN-1 | 2,3-Butanedione 2-Monoxime | BPN 0026709 | 4-Hydroxyacetophenone | JB061 | Shz 1 |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Price |
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States