JY-2 NEW
| Price | $47 | $80 | $163 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-09 |
Product Details
| Product Name: JY-2 | CAS No.: 339103-05-8 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2026/06/09 |
Product Introduction
Bioactivity
| Name | JY-2 |
| Description | JY-2 is an orally active and selective forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity and inhibits FoxO1 transcription.JY-2 can be used to study psoriasis and diabetes. |
| In vitro | JY-2, at concentrations ranging from 10 to 100 μM for 24 hours, reduces palmitic acid induced lipotoxicity in HepG2 and INS-1 cells [1]. |
| In vivo | JY-2 exhibits anti-diabetic effects in mice, administered orally at doses of 50-200 mg/kg, either three times over two days or daily for 4 weeks [1]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : < 1.32 mg/mL (4.52 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 13.16 mg/mL (45.05 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1.32 mg/mL (4.52 mM), Solution. |
| Keywords | Forkhead box protein O1 (FOXO1) |
| Inhibitors Related | RLX HCl | SB 699551 | SB 699551 dihydrochloride | DC-Y13-27 | α-Lipoic Acid sodium | Piperacetazine | Broussochalcone A | AS1842856 | kaempferide | Chlorzoxazone | RLX | Conessine |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Anti-Diabetic Compound Library | Inhibitor Library | Orally Active Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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