LIT-001 NEW
| Price | $52 | $123 | $198 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: LIT-001 | CAS No.: 2245072-21-1 |
| Purity: 97.67% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | LIT-001 |
| Description | LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM. |
| In vitro | In the in vitro signal transduction experiment, LITL-001 is an unbiased OT-R agonist, acting on the two main signal transduction pathways of this receptor, with slight antagonistic effect on V1a and agonist effect on V1b receptor, only observed at high concentration. |
| In vivo | LIT-001 (10-20 mg/kg; i.p.) alleviates core symptoms of autism spectrum disorders (ASD) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (7.74 mM), Sonication is recommended. DMSO : 247 mg/mL (382.53 mM), Sonication is recommended. |
| Keywords | vasopressin | V1a | spectrum | social | receptor | OxytocinReceptor | oxytocin receptor | OXTR | OT-R | nonpeptide | nonbiased | LIT-001 | LIT001 | LIT 001 | interaction | Inhibitor | inhibit | disorders | autism |
| Inhibitors Related | L-368,899 hydrochloride | Atosiban acetate | SSR126768A | Lysipressin | L-371,257 | Oxytocin | Carbetocin | Atosiban | Carbetocin acetate | PF3274167 | Oxytocin acetate | WAY-267464 |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | NO PAINS Compound Library | Endocrinology-Hormone Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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