Product Details
| Product Name:
MK-0429 |
CAS No.:
227963-15-7 |
| Supply Ability:
10g |
Release date:
2026/07/27 |
Product Introduction
Bioactivity
| Name | MK-0429 |
| Description | MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM). |
| In vivo | MK-0429 is safe and efficacious in obviously reducing melanoma metastasis in the lungs. MK-0429 (100 or 300 mg/kg, p.o., twice daily b.i.d., 2 weeks) decreases metastatic tumor colony formation and area in the lungs [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (7.51 mM), Sonication is recommended. DMSO : 250 mg/mL (568.82 mM), Sonication is recommended.
|
| Keywords | αvβ3 integrin | MK-0429 | MK0429 | MK 0429 | L000845704 | L 000845704 |
| Inhibitors Related | K34c hydrochloride | Cucurbitacin B | Tirofiban hydrochloride monohydrate | (R)-Leucic acid | Lifitegrast | Cyclo(-RGDfK) | ADH-503 | Elsibucol | CLT-28643 | Bestatin hydrochloride | Gantofiban | 2-hydroxy Flutamide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
-
CAS:1032349-77-1
$2785.00
-
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$40.00
|
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-07-14 |
|
|
$5.00
|
VIP3Y
|
Henan Fengda Chemical Co., Ltd
|
2026-08-06 |
|
|
|
VIP3Y
|
Shandong Hanjiang Chemical Co., Ltd
|
2026-06-25 |