MK-8353 NEW
| Price | $74 | $158 | $286 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: MK-8353 | CAS No.: 1184173-73-6 |
| Purity: 96.15% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | MK-8353 |
| Description | MK-8353 (SCH900353) is a potent, selective, and orally available inhibitor of ERK1/2 with IC50 values of 23.0 nM and 8.8 nM, respectively. |
| In vitro | MK-8353 is a potent, selective, and orally available ERK1/2 inhibitor with IC50 values of 23.0 nM and 8.8 nM, respectively; it exhibits antitumor activity. |
| In vivo | MK-8353 causes at least 50% tumor growth inhibition or regression in 83% of the animal models bearing different tumor cells[1]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (14.45 mM), Solution. 10% DMSO+90% Saline : < 10 mg/mL (14.45 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 150 mg/mL (216.81 mM), Sonication is recommended. |
| Keywords | SCH-900353 | SCH 900353 | MK-8353 | MK8353 | MK 8353 | Inhibitor | inhibit | Extracellular signal regulated kinases | ERK2 | ERK1 | ERK |
| Inhibitors Related | TBHQ | Urea | L-Cysteine | Gum arabic | β-Glycerophosphate disodium salt pentahydrate | Lactose | Lidocaine hydrochloride | Tauroursodeoxycholate | Propoxur | Gluconate Calcium | Gluconate sodium | Nisin Z |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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