Product Details
| Product Name:
Nelonicline |
CAS No.:
1026134-63-3 |
| Supply Ability:
10g |
Release date:
2026/04/20 |
Product Introduction
Bioactivity
| Name | Nelonicline |
| Description | Nelonicline is a selective agonist of neuronal nicotinic receptors. |
| In vivo | Nelonicline (0.03 mg/kg) treatment, has no significant effect on LIDs. The effect of Nelonicline (1.0 mg/kg) is also tested for its ability to reduce LIDs at a higher dose of L-dopa (15 mg/kg)/carbidopa (3.75 mg/kg). The higher dose of L-dopa leads to greater LID scores in vehicle-treated monkeys. Nelonicline treatment reduces LIDs by 70%, after the morning dose of L-dopa and 60% after the afternoon dose. The effect of Nelonicline is most pronounced during the latter weeks, possibly because of a greater decline with continued drug treatment. Nelonicline (0.10 mg/kg)treatment, decreases LIDs by ~40%, while the 0.30 and 1.0 mg/kg Nelonicline doses decrease LIDs up to ~60%. These data indicate that Nelonicline would be useful as an antidyskinetic drug in Parkinson's disease. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Neuronal nicotinic receptor | Nelonicline | AdenosineReceptor | Adenosine Receptor | ABT126 | ABT 126 |
| Inhibitors Related | Adiphenine hydrochloride | Levamisole hydrochloride | Urethane | Hexamethonium Bromide | Ribavirin | Adenine | Inosine | Theobromine | Mitotane | N,N-Dicyclohexylcarbodiimide | Arecoline | Doxofylline |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States