NMS-P715 NEW
| Price | $72 | $98 | $155 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: NMS-P715 | CAS No.: 1202055-32-0 |
| Purity: 99.84% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | NMS-P715 |
| Description | NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM). |
| In vitro | NMS-P715 (1 μM) inhibits the proliferation of HCT116 cells. And it causes mitotic acceleration in U2OS cells overexpressing YFP-α-tubulin, induces aneuploidy. NMS-P715 (0.5, 1 μM) affects mitotic checkpoint complex (MCC) stability and cdc20 ubiquitylation[1]. |
| In vivo | NMS-P715 (90 mg/kg, p.o.) is well tolerated and causes no signs of body weight loss or other overt toxicities in an A2780 ovary carcinoma xenograft model[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 0.59 mg/mL (0.87 mM), Solution. DMSO : 5.89 mg/mL (8.7 mM), Sonication is recommended. |
| Keywords | NMS-P-715 | NMS-P715 | NMSP715 | NMS-P 715 | NMS P715 | NEK6 | Mps1 | Monopolar spindle 1 | MELK | Inhibitor | inhibit | CK2 | CaseinKinase | Casein Kinase |
| Inhibitors Related | Phosphocreatine disodium hydrate | TBCA | Vemurafenib | Ellagic acid | Casein | Takinib | NG25 | Phosphocreatine disodium | RMM-46 | Oleanolic Acid | Sodium new houttuyfonate | LY294002 |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Active Compound Library | MAPK Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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