Product Details
| Product Name:
PD-307243 |
CAS No.:
313533-41-4 |
| Supply Ability:
10g |
Release date:
2026/07/08 |
Product Introduction
Bioactivity
| Name | PD-307243 |
| Description | PD-307243 is a small-molecule hERG potassium channel activator that enhances hERG current in a concentration-dependent manner. It significantly slows both channel inactivation and deactivation processes. By modulating hERG channel gating kinetics, PD-307243 increases IKr current and is widely used in cardiac electrophysiology and arrhythmia mechanism studies. |
| In vitro | Method: Whole-cell patch-clamp recordings were performed in CHO cells stably expressing hERG channels following treatment with 3 or 10 μM PD-307243.
Rresult: PD-307243 induced instantaneous hERG current with little decay at membrane potentials from ?120 to ?40 mV.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | PD-307243 | PD 307243 |
| Inhibitors Related | Minoxidil sulfate | Uridine 5'-monophosphate disodium salt | Hydrochlorothiazide | 1,8-Cineole | Tetraethylammonium bromide | Tetraethylammonium chloride | Cesium chloride | Chenodeoxycholic acid | 4-Aminopyridine | 2,2,2-Trichloroethanol | Nifedipine | Indapamide |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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