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Postion:Product Catalog >PD-321852
PD-321852
  • PD-321852

PD-321852 NEW

Price $1670 $2180 $2800
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-21

Product Details

Product Name: PD-321852 CAS No.: 622856-21-7
Supply Ability: 10g Release date: 2026/05/21

Product Introduction

Bioactivity

NamePD-321852
DescriptionPD-321852 is a small-molecule Chk1 inhibitor, which potentiates gemcitabine-induced clonogenic death in a panel of pancreatic cancer cell lines and evaluated the relationship between endpoints associated with Chk1 inhibition and chemosensitization. Gemcitabine chemosensitization by minimally toxic concentrations of PD-321852 ranged from minimal (<3-fold change in survival) in Panc1 cells to >30-fold in MiaPaCa2 cells. PD-321852 inhibited Chk1 in all cell lines as evidenced by stabilization of Cdc25A; in combination with gemcitabine, a synergistic loss of Chk1 protein was observed in the more sensitized cell lines.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsPD321852. | PD-321852 | PD321852 | PD0321852 | PD 321852
Inhibitors RelatedRabusertib | CCT245737 | Tuvusertib | Prexasertib | PD0166285 | CHK1-IN-3 | CHK1-IN-4 hydrochloride | Protein kinase inhibitor 6 | Prexasertib dihydrochloride | ANI-7 | BX795 | M2I-1

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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