PGS-IN-1 NEW
| Price | $44 | $98 | $156 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-26 |
Product Details
| Product Name: PGS-IN-1 | CAS No.: 102271-49-8 |
| Purity: 99.67% | Supply Ability: 10g |
| Release date: 2026/05/26 |
Product Introduction
Bioactivity
| Name | PGS-IN-1 |
| Description | PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM). |
| In vitro | PGS-IN-1 is the trans isomer of the synthesized α-benzulidene-γ-butyrolactone. PGS-IN-1 exhibits potent anti-inflammatory and PGS inhibitory activity with IC50 of 0.28 μM[1]. PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase with IC50 of 1.05 μM[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 55 mg/mL (181.87 mM), Sonication is recommended. 10% DMSO+90% Saline : 2.5 mg/mL (8.27 mM), Sonication is recommended. |
| Keywords | ProstaglandinReceptor | prostaglandin synthetase (PGS) | Prostaglandin Receptor | Prostaglandin E synthase | PGS-IN-1 | PGSIN1 | PGS IN 1 | PGE synthase | LOX | Lipoxygenase | KME4 | KME 4 | Inhibitor | inhibit | 5-Lipoxygenase |
| Inhibitors Related | Caffeic Acid | Bismuth Subsalicylate | Tranilast | 5-LOX inhibitor | Phenidone | 4-Aminosalicylic acid | Rutin | NNK | Malotilate | 5-Aminosalicylic Acid | Rebamipide | p-Hydroxycinnamic acid |
| Related Compound Libraries | Ferroptosis Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Antioxidant Compound Library | Inhibitor Library | Metabolism Compound Library | Lipid Metabolism Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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