Product Details
| Product Name:
PGS-IN-1 |
CAS No.:
102271-49-8 |
| Purity:
99.67% |
Supply Ability:
10g |
| Release date:
2026/05/25 |
Product Introduction
Bioactivity
| Name | PGS-IN-1 |
| Description | PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM). |
| In vitro | PGS-IN-1 is the trans isomer of the synthesized α-benzulidene-γ-butyrolactone. PGS-IN-1 exhibits potent anti-inflammatory and PGS inhibitory activity with IC50 of 0.28 μM[1]. PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase with IC50 of 1.05 μM[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 55 mg/mL (181.87 mM), Sonication is recommended.
10% DMSO+90% Saline : 2.5 mg/mL (8.27 mM), Sonication is recommended.
|
| Keywords | ProstaglandinReceptor | prostaglandin synthetase (PGS) | Prostaglandin Receptor | Prostaglandin E synthase | PGS-IN-1 | PGSIN1 | PGS IN 1 | PGE synthase | LOX | Lipoxygenase | KME4 | KME 4 | Inhibitor | inhibit | 5-Lipoxygenase |
| Inhibitors Related | Caffeic Acid | Bismuth Subsalicylate | Tranilast | 5-LOX inhibitor | Phenidone | 4-Aminosalicylic acid | Rutin | NNK | Malotilate | 5-Aminosalicylic Acid | Rebamipide | p-Hydroxycinnamic acid |
| Related Compound Libraries | Ferroptosis Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Antioxidant Compound Library | Inhibitor Library | Metabolism Compound Library | Lipid Metabolism Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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United States