S55746 hydrochloride NEW
| Price | $632 | $822 | $1410 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2025-07-21 |
Product Details
| Product Name: S55746 hydrochloride | CAS No.: 1448525-91-4 |
| Supply Ability: 10g | Release date: 2025/07/21 |
Product Introduction
Bioactivity
| Name | S55746 hydrochloride |
| Description | S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity. |
| In vitro | S55746 selectively induces apoptosis through BCL-2 inhibition in a BAX/BAK-dependent manner.S55746 (0-1 μM) potently and selectively induces cell death. |
| In vivo | S55746 is a highly efficacious and well-tolerated BCL-2 inhibitor, orally active even at doses up to 300 mg/kg. In RS4 and Toledo models, S55746 (20-100 mg/kg, p.o.) inhibits xenograft growth in a time- and dose-dependent manner. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | S-55746 Hydrochloride | S-55746 hydrochloride | S55746 Hydrochloride | S55746 hydrochloride | S 55746 Hydrochloride | BLC-201 | BLC201 | BLC 201 | Bcl-xL | Bcl-2 |
| Inhibitors Related | Gossypol (acetic acid) | (S)-(+)-Ibuprofen | Allethrin | Erianin | Navitoclax | Gossypol | Triacetylresveratrol | Diphenyl disulfide | Lisaftoclax | Venetoclax | Sonrotoclax TFA | Thymoquinone |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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