Product Details
| Product Name:
SKLB-23bb |
CAS No.:
1815580-06-3 |
| Purity:
97.58% |
Supply Ability:
10g |
| Release date:
2026/07/14 |
Product Introduction
Bioactivity
| Name | SKLB-23bb |
| Description | SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability. |
| In vivo | In vivo efficacy evaluations of colorectal HCT116, acute myelocytic leukemia MV4-11, and B cell lymphoma Romas xenografts, SKLB-23bb more effectively inhibited the tumor growth than SAHA even at a 4-fold reduced dose or ACY-1215 at the same dose. SKLB-23bb is a potent oral anticancer candidate for selective HDAC6 inhibitor. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 32 mg/mL (80.72 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.04 mM), Sonication is recommended.
|
| Keywords | SKLB-23bb | SKLB23bb | SKLB 23bb | Inhibitor | inhibit | Histone deacetylases | HDAC6 | HDAC |
| Inhibitors Related | Panobinostat | Theophylline monohydrate | Valproic acid sodium salt | Methoxyacetic acid | Sodium 4-phenylbutyrate | Acefylline | Manganese chloride (tetrahydrate) | Curcumin | Valproic Acid | Sodium butanoate | 4-Phenylbutyric acid | Theophylline |
| Related Compound Libraries | DNA Damage & Repair Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Epigenetics Compound Library | Chromatin Modification Compound Library | Anti-Breast Cancer Compound Library | Microtubule-Targeted Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$928.00
|
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-07-14 |
|
|
$1.00
|
VIP9Y
|
Career Henan Chemical Co
|
2019-07-06 |
United States