SMU127 NEW
| Price | $548 | $1850 |
| Package | 1mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: SMU127 | CAS No.: 903864-87-9 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | SMU127 |
| Description | SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer. |
| In vitro | It induces NF-κB signaling in cells expressing human TLR2 (EC50= 0.55 μM) but not cells expressing human TLR3, -4, -5, -7, or -8 when used at concentrations ranging from 0.1 to 100 μM. SMU127 induces the production of TNF-α in isolated human peripheral blood mononuclear cells (PBMCs) when used at concentrations ranging from 0.01 to 1 μM. |
| In vivo | In vivo, SMU127 (0.1 mg/animal) reduces tumor volume in a 4T1 murine mammary carcinoma model. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMF:PBS (pH 7.2) (1:4) : 0.2 mg/mL (0.59 mM), Sonication is recommended. DMSO : Slightly soluble DMF : 1 mg/mL (2.96 mM), Sonication is recommended. |
| Keywords | SMU-127 | SMU127 | SMU 127 |
| Inhibitors Related | Kaolin | Fluorene | Undecane | Ethyl palmitate | Gum arabic | Hydroxychloroquine | Benzyl alcohol | 1,8-Cineole | Dodecane | 1,4-Naphthoquinone | Tributyrin | Glucosamine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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