Tiotidine NEW
| Price | $53 | $119 |
| Package | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2025-07-19 |
Product Details
| Product Name: Tiotidine | CAS No.: 69014-14-8 |
| Supply Ability: 10g | Release date: 2025/07/19 |
Product Introduction
Bioactivity
| Name | Tiotidine |
| Description | Tiotidine is a selective histamine H2-receptor antagonist (pA2=7.3-7.8 for guinea-pig right atrium). |
| In vitro | Tiotidine effectively neutralizes the increase in contractile force facilitated by H2, leaving the negative inotropic responses by H2 unchallenged. It also mitigates the effects of histamine on the A-V node, which include lengthening of the P-R interval and A-V block, at a concentration of 2.5 x 10(-7) M. Furthermore, tiotidine acts as a competitive antagonist against the positive chronotropic effects of histamine, presenting an apparent dissociation constant of 30 μM (23-38 μM). Additionally, tiotidine displays inverse agonist activity in U-937 cells by reducing basal cAMP levels. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Tiotidine | ICI-125211 | ICI125211 | H3 Receptor | H2 Receptor | H1 receptor |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $119.00 |
VIP4Y
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TargetMol Chemicals Inc.
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2026-05-11 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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