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Postion:Product Catalog >ZD-0892
ZD-0892
  • ZD-0892

ZD-0892 NEW

Price $71 $176 $290
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-06

Product Details

Product Name: ZD-0892 CAS No.: 171964-73-1
Purity: 99.53% Supply Ability: 10g
Release date: 2026/05/06

Product Introduction

Bioactivity

NameZD-0892
DescriptionZD-0892 is a selective and potent inhibitor of neutrophil elastase, targeting human neutrophil elastase and porcine pancreatic elastase with Kis of 6.7 nM and 200 nM, respectively.
In vitroNeutrophils incubated with ZD-0892 (20μM) for 1 hour were found to be resistant to superoxide, hypochlorite, hydrogen peroxide, hydroxyl radical and peroxynitrite-mediated degradation and had no effect on the formation of these oxidants by activated neutrophils.[3]
In vivoAdministration of ZD0892 to DBA/2 mice infected with EMC virus reduces myocardial elastolytic activity and coronary microvascular perfusion injury.ZD0892 reduces the pathological severity of myocardial lesions associated with viral myocarditis in mice[1].ZD-0892 reverses advanced pulmonary vascular disease produced in rats[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 150 mg/mL (300.29 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (8.01 mM), Sonication is recommended.
KeywordsZD-0892 | ZD0892 | ZD 0892 | SerineProtease | Serine Protease | neutrophil elastase | Human neutrophil elastase
Inhibitors RelatedPMSF | AEBSF hydrochloride | Imidazole | Subtilisin | p-Aminobenzamidine dihydrochloride | Chymotrypsin | Proteinase K | Aprotinin | Ac-Ala-OH | Trypsin | FOY 251 | Benzamidine hydrochloride
Related Compound LibrariesBioactive Compound Library | Protease Inhibitor Library | Drug Repurposing Compound Library | Inhibitor Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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