ZM223 NEW
| Price | $70 | $161 | $236 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-04 |
Product Details
| Product Name: ZM223 | CAS No.: 2031177-48-5 |
| Purity: 99.73% | Supply Ability: 10g |
| Release date: 2026/07/04 |
Product Introduction
Bioactivity
| Name | ZM223 |
| Description | ZM223 is an inhibitor of NEDD8 activating enzyme (NAE). |
| In vitro | ZM223 (0.1-1 μM) inhibits cell growth with IC50s of 100 and 122 nM in HCT-116 and U-2OS cancer cells, respectively. ZM223 (0.1-1 μM) dose-dependently reduces the level of NEDD8 and accumulation of the UBC12 protein thereby reducing the subsequent NEDD8-UBC12 complex[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (6.57 mM), Sonication is recommended. DMSO : 80 mg/mL (159.19 mM), Sonication is recommended. |
| Keywords | ZM223 | ZM 223 | NEDD8 activating enzyme (NAE) | NAE | E3Enzyme | E3 Enzyme | E2Enzyme | E2 Enzyme | E1Enzyme | E1 Enzyme |
| Inhibitors Related | T521 | PYZD-4409 | NAcM-OPT | Nutlin-3 | Yucasin | BC-1293 | EN219 | NSC232003 | Auxinole | Indole-3-carbinol | Idasanutlin | TRIM25 ligand-1 |
| Related Compound Libraries | Bioactive Compound Library | Ubiquitination Compound Library | Post-Translational Modification Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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