Mouse DNAM-1 / CD226 Protein, His Tag (SPR verified)
分子別名(Synonym)
DNAM1,CD226,PTA1
表達區(qū)間及表達系統(Source)
Mouse DNAM-1, His Tag (DN1-M52H5) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - His 250 (Accession # Q5DW69-1).
Predicted N-terminus: Glu 19
蛋白結構(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 28.1 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
DNAX輔助分子1(DNAM-1)是一種單程I型膜蛋白,也被稱為CD226抗原和血小板和T細胞活化抗原1(PTA1),其中含有2個Ig樣C2型(免疫球蛋白樣)結構域。DNAM-1是一種約65 kDa的糖蛋白,在自然殺傷細胞、血小板、單核細胞和T細胞亞群的表面表達。DNAM-1介導細胞與攜帶其配體CD112和CD155的其他細胞的粘附,并將DNAM-1與抗體交聯導致細胞活化。此外,DNAM-1可以與PVR和PVRL2相互作用。
關鍵字: DNAM1;DNAM1蛋白;CD226重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下擁有品牌ACROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。