Product Name：PDpep1.3
CAS No.：2942277-55-4
Synonyms：抑制劑多肽PDpep1.3
Catalog No.：220P024
Brand：Typeptide Biotech（肽研生物）
Description：PDpep1.3是一種肽類 α-突觸核蛋白 (α-synuclein) 抑制劑多肽，是由12個(gè)氨基酸組成的多肽，可破壞 α-synuclein 與 CHarged Multivesicular body Protein 2B (CHMP2B) 之間的直接相互作用。從而，PDpep1.3 恢復(fù)內(nèi)吞體和溶酶體的降解功能，降低了 α-synuclei 的蛋白水平和 α-synuclei 聚集，并保護(hù)多巴胺能神經(jīng)元免受 α-synuclei 介導(dǎo)的退化。PDpep1.3 可用于對(duì)神經(jīng)退行性疾病和蛋白質(zhì)-蛋白質(zhì)相互作用的研究。
PDpep1.3 is a peptide inhibitor of alpha synuclein, consisting of 12 amino acids, which can disrupt the direct interaction between alpha synuclein and CHarged Multidimensional Body Protein 2B (CHMP2B). Thus, PDpep1.3 restores the degradation function of endosomes and lysosomes, reduces the protein level and aggregation of alpha synuclei, and protects dopaminergic neurons from alpha synuclei mediated degeneration. PDpep1.3 can be used for the study of neurodegenerative diseases and protein-protein interactions.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | DEEIERQLKALG |
Sequence(3-letter code) | H-Asp-Glu-Glu-Ile-Glu-Arg-Gln-Leu-Lys-Ala-Leu-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C59H101N17O22 |
Molecular Weight | 1400.53 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： PDpep1.3;抑制劑多肽PDpep1.3;2942277-55-4;多肽;多肽工廠;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。