Biotinylated Human IL-7 R alpha / CD127 Protein, Fc,Avitag?
分子別名（Synonym）
IL7Ra,CD127
表達區(qū)間及表達系統(tǒng)（Source）
Biotinylated Human IL-7 R alpha Protein, Fc,Avitag (IL7-H82F9) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Asp 239 (Accession # P16871-1).
蛋白結構（Molecular Characterization）
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 53.5 kDa. the protein migrates as 67-75 kDa under reducing (R) condition, and >116 kDa under non-reducing (NR) condition (SDS-PAGE).
標記（Labeling）
Biotinylation of this product is performed using Avitag? technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
蛋白標記度（Protein Ratio）
Passed as determined by the HABA assay / binding ELISA.
純度（Purity）
>90% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景介紹
白細胞介素-7受體α亞基（IL7Ra）亦稱為CD抗原CD127，屬于I型細胞因子受體家族中的4型亞家族。該蛋白包含1個纖連蛋白III型結構域，廣泛表達于多種細胞類型，包括初始T細胞、記憶T細胞等。IL7Ra/CD127不僅是白細胞介素-7的受體，同時也能作為胸腺基質淋巴細胞生成素（TSLP）的受體。IL-7受體由IL7R與IL2RG組成異源二聚體，而TSLP受體則由CRLF2與IL7R構成異源二聚體。
關鍵字： IL7Ra;IL7Ra蛋白;IL7Ra重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領域提供關鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。