Product Name：Pasireotide
CAS No.：396091-73-9；396091-76-2（Hac）；1421446-02-7(diaspartate)
Synonyms：帕西瑞肽;SOM230
Catalog No.：218P051
Brand：Typeptide Biotech（肽研生物）
Description：Pasireotide是一種結(jié)構(gòu)為環(huán)六肽的生長(zhǎng)抑素類似物，序列中含有4個(gè)非天然氨基酸，作為藥物主要成分的Pasireotide適用于未進(jìn)行垂體手術(shù)或手術(shù)未治愈的庫(kù)欣氏病成年患者的治療。同Octreotide相比，Pasireotide有更長(zhǎng)的半衰期、能與更多受體結(jié)合，抑制胰腺分泌，抑制腸道蛋白水解酶的活性，通過這些機(jī)制來降低胰腺術(shù)后并發(fā)癥。
Pasireotide is a growth hormone analogue with a cyclic hexapeptide structure, containing four non natural amino acids in its sequence. As the main component of the drug, Pasireotide is suitable for the treatment of adult patients with Cushing's disease who have not undergone pituitary surgery or have not been cured by surgery. Compared with Octreotide, Pasireotide has a longer half-life, can bind to more receptors, inhibit pancreatic secretion, and suppress the activity of intestinal proteolytic enzymes, thereby reducing pancreatic postoperative complications through these mechanisms.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | cyclo[Y(Bzl)F-Hyp(Bom)-Phg-d-W-K] |
Sequence(3-letter code) | cyclo[Tyr(Bzl)-Phe-Hyp(Bom)-Phg-D-Trp-Lys] |
Peptide Structure | 
|
Molecular Formula | C58H66N10O9 |
Molecular Weight | 1047.21 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： 帕西瑞肽SOM230;1421446-02-7(diaspar;Pasireotide;396091-76-2（Hac）;396091-73-9;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。