Product Name：Pasireotide
CAS No.：396091-73-9；396091-76-2（Hac）；1421446-02-7(diaspartate)
Synonyms：帕西瑞肽;SOM230
Catalog No.：218P051
Description：Pasireotide是一種結(jié)構(gòu)為環(huán)六肽的生長抑素類似物，序列中含有4個(gè)非天然氨基酸，作為藥物主要成分的Pasireotide適用于未進(jìn)行垂體手術(shù)或手術(shù)未治愈的庫欣氏病成年患者的治療。同Octreotide相比，Pasireotide有更長的半衰期、能與更多受體結(jié)合，抑制胰腺分泌，抑制腸道蛋白水解酶的活性，通過這些機(jī)制來降低胰腺術(shù)后并發(fā)癥。
Pasireotide is a growth hormone analogue with a cyclic hexapeptide structure, containing four non natural amino acids in its sequence. As the main component of the drug, Pasireotide is suitable for the treatment of adult patients with Cushing's disease who have not undergone pituitary surgery or have not been cured by surgery. Compared with Octreotide, Pasireotide has a longer half-life, can bind to more receptors, inhibit pancreatic secretion, and suppress the activity of intestinal proteolytic enzymes, thereby reducing pancreatic postoperative complications through these mechanisms.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
關(guān)鍵字： 帕西瑞肽;Pasireotide;帕瑞肽;